Effect of cross-links on the autocatalytic polymerization of RNA-like chains

da Silva L, Mundim KC, Tsallis C

PHYSICA A
259: (3-4) 415-429 OCT 15 1998


Cited References : 42             Times  Cited: 0

Abstract:
        In order to discuss some prebiotic stages, we present computer simulations assuming an autocatalytic polymerization of RNA-like chains from a random collection of oligomers in two dimensions through an equilibrium process. In the simulations we consider the effect of the possible cross-links (non-specific weak bindings among or within the polymers), that may actually contribute to the folded shape of some real polymers, and we show that cross-linking favors the appearance of larger polymers. Furthermore, we discuss the obtained scenario with regard to some experimental results, which compare well with our numerical ones. (C) 1998 Elsevier Science B.V. All rights reserved.

KeyWords Plus:
TEMPLATE-DIRECTED REACTIONS, PREBIOTIC CHEMISTRY, POLYMERASE MODEL, LIFE, ORIGIN, ANALOGS, OLIGOGUANYLATES, OLIGOMERIZATION, REPLICATION, EVOLUTION

Addresses:
da Silva L, Ctr Brasileiro Pesquisas Fis, Rua Xavier Sigaud 150, Urca, BR-22290180 Rio De Janeiro, Brazil.
Ctr Brasileiro Pesquisas Fis, BR-22290180 Rio De Janeiro, Brazil.
Univ Fed Bahia, Dept Fis, Salvador, BA, Brazil.

Publisher:  ELSEVIER SCIENCE BV, AMSTERDAM
IDS Number:  130UU
ISSN:  0378-4371